As a girl's name this is a pet form of Jacqueline, as in the case of Jackie Kennedy Onassis (1929–94). It was originally a boy's name, a pet form of Jack. The racing driver Jackie Stewart (b. 1939) was originally named John Young Stewart.
English: metronymic from a form of the female personal name Margaret, via Late Latin Margarita from Greek margaritēs ‘pearl’. This was borne by several early Christian saints, and became a popular female personal name throughout Europe. The vocabulary word was borrowed into Latin and Greek from a Semitic source, and is probably ultimately from Persian morvarid ‘pearl’.